Uncharted 4 Story DLC might explore the adventures of Sam and Sully. Spoiler alert! The ending of Uncharted 4 showed Sam and Sully joining hands to continue their adventures. Meanwhile Nathan Drake takes off to live a normal life.
Furthermore, early sections of Uncharted 4 show a young Sam and Nathan finding there way into life as treasure hunters. The orphanage section jumped to the Prison section and we never got to see the events in the middle. According to Troy baker (the man behind Sam Drake), there are different aspects that can explored.
He followed his statement by clarifying that nothing is finalized. And if you are working with such a talented studio, its judgement must be trusted.
Troy Baker on Uncharted 4 DLC
After playing the game, I find myself really torn because a part of me wants [to see] what Sam and Sully are going to do.
I was so impressed with what Chase Austin did as young Sam that there’s a lot of me that wants to see [them] go back. We jumped from them being in the orphanage to the prison – I want to know what happened during that whole space in between.
They’re still batting about ideas, I don’t think they’ve even landed on one. Those guys are still recuperating from shipping that game. When you work with someone like Naughty Dog, you just have to trust them and I’m sure they’re going to make the right decision.
Naughty Dog uses two separate development teams. One of them is currently working on The Last of Us 2 while the other will most likely start work on Uncharted 4 story DLC soon.